For me, Windows Defender plus Malawarebytes Premium is a good combination; used it for years wit no problems. Some like Kapersky , but I am happy. I use CCleaner to clean stuff and as a mild registry cleaner, and to monitor start up, and to delete unwanted restore points. The occasional use of superantispyware finds ad aware cookies, and I occasionally use ADWCleaner if a suspicion of a address hijack is suspected. Of all the above I find MBAM Premium is the most needed - it blocks suspect websites, finds PUP’s , scans for issues , all live.
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