No, although you probably could run it from a command prompt (I don't know). Put the CD in the drive and as you say hold the shift key. If it does Autostart just close it down and run the command. If he seems to get an error message when it runs tell him to keep clicking 'Retry' (about 20-30 times) until it's finished
Apparently there's a bug that looks for a disk that it says doesn't exist e.g. when I run it on my XP Home system it asks for the XP Professional disk. If I press 'Retry' a lot then it checks all my files but it's a pain keeping having to click every few seconds. For other people it apparently runs fine. You don't have to restart at all, well I didn't.