As this a 'Powered Hub' I see no problem. A problem could theoretically arise if it were plugged in the a MoBo with other devices all making demands for power- this will slow the machine down and in extreme cases stop the computer all together.
Agree with Technotiger. It doesn't really matter if you plug it into a hub or not as far as I'm concerned it still works. The only thing that would make a difference as far as I am concerned is if you have USB 2.0 ports on the computer and the hub was USB 1.1. If so then the hub would slow the drive to a crawl and shouldn't be used.