Second drive in PIO mode.
Re-enable DMA using the Registry Editor
Run REGEDIT. Go to the following key:
It has subkeys like 0000, 0001, 0002, etc. Normally 0001 is the primary IDE channel, 0002 the secondary, but other numbers can occur under certain circumstances. Check the DriverDesc value to see which one it is.
Delete MasterIdDataChecksum or SlaveIdDataChecksum, depending on whether the device in question is attached as master or slave, but it can't actually hurt to delete both. Reboot. The drive DMA capabilities will be redetected.
Open Device Manager again and check whether the device is now actually using DMA mode. If so, congratulations, you've made it (at least until the next time Windows disables DMA).
Alternative Method—Uninstalling the Port
Uninstall the secondary IDE port
To do that, open Device Manager as follows. Right-click on My Computer, select Properties, click on the Hardware tag, click on the Device Manager button, click on the plus sign to the left of IDE ATA/ATAPI Controller, right-click on Secondary IDE Channel, click on Uninstall. Deactivating is not enough.
Reboot to make the changes active and permanent.
After booting Windows will automatically reinstall the IDE channel and the DVD (or CD) drive. This Plug-n-Play process can take a little while, so give it a minute after the boot process finishes.