My PC is intermittently not detecting the SATA drive, the two IDE drives show ok, this can happen while playing games the game will stop and the drive will not be in my computer. After a reset the drive will come back up.
Have you removed the side of the case and checked drive and power connections are secure. Could possibly be a heat related problem, try running with the side of the case off for a while, if this cures the problem you may want to consider add another case fan.
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