nope. If you have the newer ide cables, the blue connector goes to the motherboard, the black connector to the master and the grey to the slave. If all your connectors are the same colour, stick the drives on any of them.
The screws are not a problem so long as they arent so long that they go through the casing into the mechanism itself. The screws which hold your computer case on are usually about right, try one and if its ok, take that to your hardware store. You must have a good hardware store though, mine only has wood screws. You can buy packs of them from maplins.