After using the Windows Accessory programme to get rid of unwanted files, whenever I start up I get the screen message the Short cut SETUP.Ink refers to a location that is not available. How can I get rid of this message?
You've deleted a program that runs at startup, so you need to look in Start/All Programs/Startup to see if there is a program called Setup there.
If it's not there you need to un MSconfig, go to Start/Run & type MSconfig. Click the 6th tab, Startup, and look in there for an entry for Setup, and remove the tick in the box. Restart your computer and the box shouldn't pop-up.
btw If you are running XP you will get a box popping up with some guff about you have chosen Selective Startup, just click the box in the bottom left saying "do not give this warning again" and close the box.