Speaking without particular knowledge of MESH but of PC's in General[and there is no reason to think that a MESh is other wise]
There are two sizes of drive bay 5.25 wide and 3.50 wide.
PC hard drives are in the latter catagory.
a bay adaptor, is a normal piece of kit available
from components suppliers. try click here for one or get a copy of MicroMart from your news agants for lots more