"If I save Dreamweaver software...." do you mean software that you're downloading - a trial version, or even a full version of DreamWeaver?
If so, the answer's 'yes' it will work on your second computer. You can download a trial version to a folder on one machine, copy the folder to your USB drive, and install the program on both computers. It will work perfectly, but only as a trial version. Once you decide to buy a licence and activate the software it will work on the machine on which it was activated. You can't use the same licence on the second machine. At the end of the trial period (30 days) the program will stop working unless it's activated.