Ad-aware will scan your PC for files which are in its database (update regularly!). Anything it finds it will ask you if you want the items quarantined so they cannot do any harm. You can delete them later.
SpywareBlaster will protect your PC from the items in its database. Click 'Select All', then 'Protect Against Checked Items!'. Then leave it to its job. Once again, update regularly.
Spybot-Search & Destroy does a similar scan to Ad-aware, but with a different database it may find other threats.
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