Sleep IS a problem with Vista that is meant to be resolved with SP1. The best advice at the moment is to turn it off.
As far as booting problems go I don't think you can pin this one on Vista something must be wrong with the installation or your set up. I have heard of many things being blamed on Vista but not that.
As a matter of interest I have a fairly high spec Mesh machine and Vista boots up within about 40 seconds.