open drive C, or whatever drive Vista is on , navigate to the (local settings) folder in question.
right click and select "properties"
select SECURITY tab, then choose "Advanced"
Click on Owner and then Edit, current owner is probably listed as "System"
Highlight your identity and click Apply.
A window will open telling you that you have just taken ownership of this file , and that you can now edit or change permissions , click ok.
you must now close the file in question and reopen it before you can change permissions .
be careful though , this is after all a system file and any changes you may make could adversly affect your OS .