I think i've solved the open file box problem.
I found this solution on Google: click here
like on the response from another guy to that link I had to first uncheck the always "Always ask before opening this file" and run the program then restart the laptop.
So far i've re started several times and the dialogue box has not reappeared although the program loads as it appears in the system tray.
I thought i'd let you know incase someone is experiencing a similar problem and this solution might help .. although there a quite a few (see google) and some work and some don't.
The other problem i'm experiencing..well i've cleared the Autostart one ..it was my Error Repair registry cleaner which was ticked to autostart on startup in the settings. i've unchecked that...but the problem still remains with the registry editor which i believe is a MS one. In start up it's showing as permitted .. why is it being blocked??