Fonts in Linux are a minimal overhead, I'd leave them alone.
You may also want to check that you have the Microsoft standard fonts installed. I can't remember whether Mint installs them as standard or not.
If you have (for example) Comic Sans MS, you already have them. If not go to your package manager and look for msttcorefonts.
Like it or not, not having those can make browsing unpleasant, as many websites use Arial or Verdana fonts.