Wow, big subject, this one!
Firstly, you could click here and have a play with the free trial. It will get you used to layouts, although it will not teach you anything technical.
Get a copy of Net Objects Fusion 8 from a cover CD. Take the time to learn how to use it and post in Webdesign every time you need help. I or one of the other current or former NOF users will pick it up. If you get stuck trying to find a copy, I might be able to rustle one up for you!
If anyone says "use Dreamweaver" ignore them in the nicest possible way! Good though it is, it's not for beginners, believe me. It is also very expensive indeed.
Have you got free server space from your ISP? If not, sign up for some from another dedicated freespace provider such as Freewebs. This will get you started as you absolutely need server space for the constant testing!