Be careful if you decide to delete any start up programs as it is NOT always easy to find out what they do, and this could corrupt the start up sequence and cause BSOD. If you want to do this USE ACRONIS first. David
msconfig From my experience there is no harm in unticking all the start up programs. If Windows need them they will comeback as will any programs which you use and are designed to come back on restart. Clearly your anti virus should remain ticked. I think that you will find other forum members have the same experience of this and there is no harm done by unticking all items.