to start off with, have you tried the new microsoft anti-spyware download??? It's about 6.5 megs and it has found approx 20 more adware and spyware even though I use "Ad-Aware SE Professional" (paid version and not the free version).... click here for info and how to download this FREE utility!!!
Have you got a "professional" anti-virus program e.g. Norton Anti-Virus (Pro or standard!!)???