It depends on which popups they are, sideboard. If they're "ordinary" popups, PopUp Stopper from click here should do the trick. If they're Messenger Service popups, you'll have to disable the Messenger Service, instructions for your OS (which you haven't stated) can be seen if you click here
These have the facility to selectively block pop-up ads and are hugely more secure than Microsoft's Internet Explorer. With Opera, for example, this is selected from the File > Quick Preferences menu as shown under 'Quick Preferences Menu': click here
If you are using Internet Explorer on Windows pop-ups may also be spawned by adware that has been surreptitiously installed on your system.