I do not believe that your problem is due, to your system being a Mesh. If it has just started to happen of late,more than likely it could be some new software or files that have been added or even deleted.
Try a SFC /SCANNOW from the start/run command having your recovery disk at hand,and see if that helps.
If you can point to any changes that you have made of late ,try reversing ,if not do a systems restore to a date that you know was when PC running well.
If by any chance it does not change things you may have to look at IE6 for a repair as the'Page cannot be found'if regular may have a problem.Do try the above first ,then post back.