I think that you are going to have a problem with these questions because I doubt that many readers have experience with both McAfee and Trend.
It is different if you ask the same about e.g. AVG vs. Avast because, as they are free, lots of people will have tried both out.
For what it is worth I have McAfee on here and it has never let me down, is easy to configure and non-intrusive (except when a website is trying to plant a trojan etc. - even then the alerts are manageable, unlike NIS).