I use a cordless mouseman (not optical) with my Dell Inspiron 3700 and have no problems at all such as those you describe. The transmitter has a USB connector, but I use it with the PS2/USB adapter (provided by Logitech with the mouse) and plug into the PS2 port. Never the hint of a problem. Go to the Logitech site and have a look on the forums there. There is a fairly active membership with lots of postings about specific Logitech products and problems.