Like many others, my IE6 startpage has been hijacked. I have run Spybot, Adaware, SpyWareBlaster, CWShredder, Hijackthis, etc, but I am still getting a dodgy "MSN Homesearch" page addressed "res://iqsde.dll/index.html#37049".
I have manually deleted any reference to "iqsde" from the registry, but it's back again!
I had something like that quite a while ago, and from you saying 'a dodgy MSN page' it is the same one. I tried everything, and eventually I just ended up having to format, and re-install Windows XP. :-( Hope it doesn't come to that for you.
My daughter has just had this, run adaware and delete all that it finds, you say you have spy ware balster? go into tools, misc ie sttings and tick lock homepage this will stop anything changing your hpomepage (first set your homepage to what want in ie of course)