Most people use one of two options for doing this:
First is to use Frames, which is perhaps easier but lots of designers tend not to like them anymore.
Second is to use a table, which may be a bit more work but should give a clean site overall.
As for Music, then yes fairly easy to put in as an event when something happens. You need to embedd the object. Sorry haven't got Dreamweaver to hand at the moment to give more details.