OS is ME. I've run Spybot and found Haxdoor and DSO Exploit on my computer. I've "fixed" these with Spybot, but they keep re-appearing. eg. I disconnected from internet, switched off Sys Restore and ran Spybot, which found the and then fixed them. Then I restarted computer and ran Spybot again and these things are shown again!
I've also found in last 48hrs that one of my email addresses has been "hijacked" and emails of uncertain nature are apparently being sent from my address. Found out because I received one in my other email inbox.