So I guess it also happens when you use the Realtek equaliser?
Have you tried with another media player? I sometimes find a similar problem to yours when I use Windows Media Player with it's equaliser on/tweaked.
Another reason I can think of is that those speakers aren't powerful enough to handle the 'tweaked' sound, or even extremes of highs & lows. Try to swap with another set if possible to rule them out.
Btw, speakers don't need drivers to function - it's the soundcard that does. Check if you have the latest. If not, download the latest, install them, reboot & see if it makes a difference. G