Everytime I go to a website, a pop-up stating "We're popular! Everybody loves us! Don't you? Click ENABLE to get us back!"
I really don't want this popping up all the time, so is there any way to delete it forever?
I thought that I had got rid of it, and I believe it is a Serif product, but I am not sure.
Which browser (Firefox, IE) are you using? have you set browser in Options to not allow popups? Do you have any Adblocker addons? You need to give us more details so that we can advise how to avoid getting it and similar again once you have cleaned with cCleaner.
I use SpywareBlaster (free program) and AdBlock Plus with Firefox Browser.