Hi, not a 'registry' man myself, but all these files are driver files - if she has XP then perhaps a System Restore might do the trick. Good luck ...... anyway, someone more knowledgable than I will come to your aid I am sure. lol
Is the registry cleaner (which one?) saying that these are orphaned registry entries? I.E. they are listed in the registry but are no longer present on the PC. If so, it is safe to let the registry cleaner remove the invalid registry entries.