You will not have any problems with OEM software. If it's Microsoft software and has not been "Activated" to a PC, then it will activate and if you wish "Register" as well.
Because it's OEM, then once you activate it, it should stay with the PC that you activate on, therefore not transferable to any new PC you buy.
Other than that it's the same as the full retail version. If buying from anyone, check that it's a genuine product and unused.