I tend to 'trial' most of the free or limited offer 'cleaners', usually at the same time, so as to see what occurs on the computers that I use for this purpose.
Most will have there own qwerks and problems, if not used with consideration, especially those that suggest a paid upgrade is essential. Fortunately, I am able to get some of these upgrades for free, which still convinces me most times, that even the Pro versions are suspect in doing a full job intended.
CCleaner as always been a firm favourite of mine, right from its introduction. Never had any problems with that product, and that includes any registry fixes. Suggest that you keep it on your computer, and regular check for latest updates.