Judging by the Asus UK website (click here) all the P5VD2 series have PCIe x16 graphics cards slots. (But I can't see a NVM/S model there.) The slot is what establishes compatibilty and PCIe x16 cards are the norm at present. If you're asking for a recommendation for a specific card, that's trickier, and probably beyond my off-the-top-of-my-head competence. It might be necessary to know what games you'd like to play - some are very demanding (and might need a more powerful CPU as well). HD playback is less of a problem.