Yes you can, I have done just this myself in the past. Three things you should be aware of:
If you save a file using the new version, you may not be able to open it, or it may have some feature disabled, if you open it in the old version. You can overcome this if you save in the old file format, when using the new version (but you will get a warning that some features will disappear).
If you write code in the VBA editor, you may get a similar problem, but with the added complication of not necessarily having the correct versions of Office set up in the References. If you don’t write code then this need not concern you.
Access can get its knickers in a twist if you set up digital signatures and try to work on a database (and underlying code) and swap between Office versions. You can suddenly find you can no longer edit your code.
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