More detail please. What system are you running? What have you done try to delete this virus ,you just say Norton way does that mean you have not tried any other way than with Norton?
How did this infection happen and apart from the fact you say you cannot get into "Safe Mode" - -what happens when you try to get into "safe Mode" and how are you trying to get into " Safe Mode"??
All the above which you have not stated will help us to help you.