The most irritating popup ever was last week on BT Openworld homepage with a large size popup (can't remember what it was advertising) together with a rendition of the "Goodbye" song from the Sound of Music. The ad. failed in its mission because, as I've said, I can't remember anything about what it was advertising - its the same with all of these intrusions.
When will the advertisers and all associated companies realise that you don't gain customers by irritating them? My company does a fair amount of advertising work but a big no-no as far as I'm concerned is anything that antagonises the potential customer.